Skip to main content

Cookies are small text files that are place on your computer by websites that you visit. They are widely used in order to make websites work, or work more efficiently, as well as to provide information to the owners of the site. The table below explains the cookies we use and why.

careers

Senior Principal Scientist, Translational Development, Pancreatic Cancer Disease Lead page is loaded

Senior Principal Scientist, Translational Development, Pancreatic Cancer Disease Lead

locations
Princeton - NJ - US
Cambridge Crossing - MA - US
time type
Full time
posted on
Posted 3 Days Ago
job requisition id
R1590069

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Translational Medicine at BMS

Translational Medicine is a department within the Research organization that facilitates the transition of drug candidates from early to late-stage clinical development, their approval and life cycle management. Early-stage translational development activities enable rational determination of dose-schedule and responsive patient populations, based on deep understanding of drug mechanism of action and disease segments.

Late-stage translational development activities build upon the early work, additionally exploring mechanisms of resistance, rational drug combinations and product differentiation. The late-stage translational development function is responsible for the translational strategies to support the development of BMS therapies after clinical proof-of-concept studies, including but not limited to regulatory submissions and life-cycle management.

Translational disease strategies in gastrointestinal (GI) malignancies are derived from long term investments in developing data and deep expertise in disease biology, patient segmentation and therapeutic resistance to inform science driven strategies for the development of the GI Oncology pipeline.

This position is an On-Site position located in either Princeton, NJ or Cambridge, MA.

Position Description:

  • Develops and executes translational disease strategy in the pancreatic cancer (PC) area with deep disease expertise
  • Leads and oversees execution of disease strategy including but not limited to various aspects of patient selection strategies
  • Serves as scientific expert in generating novel hypotheses for actionable biology based on novel discoveries integrating disease work with literature and deep expertise in PC biology
  • Manages cross-functional disease project teams with key interfaces in IT, bioinformatics, data sciences, biostatistics, external collaborators, contractors, other disease strategy leads and asset leads
  • Maintains relationship with physician scientists for identifying new opportunities and for gaining disease insights
  • Identifies needs, gaps and translational disease questions and applies knowledge across all assets in BMS portfolio in the PC area
  • Leads small and large collaborations with academia and industry partners to identify biobanks, clinical trials and existing databases to collate multi-parameter genomic, immune and clinical datasets to mine for novel biomarkers of unmet need patients in conjunction with computational biologists, data scientists and statisticians
  • Collaborates and guides bioinformatics partners on biological questions to deliver biomarkers and biological understanding from whole transcriptome, whole exome, and/or whole genome data, immune profile and single-cell data to support drug discovery and development in the PC space
  • Manages relationships with key internal stakeholders including Regulatory, Clinical,  Commercial, Medical Affairs & Communications and external collaborators to develop translational analysis plans and timelines, communicate analysis results
  • Represents the Solid Tumor Translational Development function at various internal meetings and provide domain knowledge and disease expertise to cross-functional teams
  • Directs and supports publications in high quality scientific, technical or medical journals

Qualifications:

  • PhD degree in a relevant field (e.g. molecular biology, cancer biology, human genetics)
  • 4+ years post-PhD experience, with demonstrated scientific leadership in integrating, analyzing and interpreting multimodal translational data in an academic and/or industry setting
  • Strong background in human cancer genetics, tumor biology & immunology, genomics/multi-omics with deep understanding of tumor-intrinsic and tumor-extrinsic mechanisms driving cancer development and therapeutic resistance
  • Extensive knowledge of high-content biomarker platforms and good understanding of the current clinical practice in Pancreatic Cancer.
  • Ability to work in a fast-paced environment with rapidly changing and competing priorities and ambiguity
  • Strong team player with the ability to work in cross-functional teams. Excellent communication and collaboration skills
  • Prior experience with clinical trials preferred
  • Strong track record of high-quality scientific publications in relevant fields

#LI-ONSITE

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Similar Jobs (2)

locations
3 Locations
time type
Full time
posted on
Posted 22 Days Ago

About Us

Logo

Data Privacy Link

We’re creating innovative medicines for patients fighting serious diseases. We’re also nurturing our own diverse team with inspiring work and challenging career options. No matter the role, each one of us makes a contribution. And that makes all the difference.

Follow Us
© 2025 Workday, Inc. All rights reserved.